Evaluation of three portable blood lactate analysers: Lactate Pro, Lactate Scout and Lactate Plus

Eur J Appl Physiol. 2010 Jun;109(3):551-9. doi: 10.1007/s00421-010-1379-9. Epub 2010 Feb 10.

Abstract

Three portable blood lactate analysers, Lactate Pro (LP), Lactate Scout (LS) and Lactate Plus (L(+)), were evaluated. Analyser reliability and accuracy was assessed. For reliability, intra- and inter-analyser comparisons demonstrated that the LP (intra-TE = 0.5 mM, inter-TE = 0.4 mM) and L(+) (intra-TE = 0.4, inter-TE = 0.4 mM) displayed greater overall reliability than the LS (intra-TE = 1.0, inter-TE = 0.8 mM). At BLa < 4.0 mM, the LP (intra-TE = 0.1 mM) demonstrated greater reliability than the LS (intra-TE = 0.5 mM) and L(+) (intra-TE = 0.4 mM). At BLa > 8.0 mM, the LP (intra-TE = 0.5 mM, inter-TE = 0.4 mM) and L(+) (intra- and inter-TE = 0.4 mM) displayed greater reliability than the LS (intra-TE = 1.1 mM, inter-TE = 0.9 mM). For accuracy, the L(+) (SEE = 0.6 mM) compared more favourably to the LP than the LS (SEE = 1.1 mM). At BLa approximately 1.0-18.0 mM, the LS produced values that were up to 0.9 mM higher than the LP; the L(+) produced BLa that were within +/-0.1 mM. All portable analysers tended to under-read the ABL 700 analyser. The suitability of the LP and L(+) as accurate analysers is supported by strong correlations (r = 0.91 and r = 0.94) and limits of agreement <or=2.1 mM. This study showed that the LP and L(+), compared well to each other, displayed good reliability and accuracy when compared to a laboratory-based analyser. Although the LS also displayed relatively good reliability, it was not as reliable or accurate as the LP or L(+).

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomarkers / blood
  • Blood Chemical Analysis / instrumentation*
  • Blood Gas Analysis / instrumentation
  • Electrochemical Techniques
  • Equipment Design
  • Female
  • Humans
  • Lactic Acid / blood*
  • Linear Models
  • Male
  • Observer Variation
  • Predictive Value of Tests
  • Reagent Strips
  • Reproducibility of Results

Substances

  • Biomarkers
  • Reagent Strips
  • Lactic Acid