Primary peritoneal spindle cell sarcoma presented with massive ascites: a case report

J BUON. 2009 Oct-Dec;14(4):721-3.

Abstract

Soft tissue sarcomas (STSs) are a heterogeneous group of rare neoplasms originating from the embryonic mesoderm and mesenchymal cells. Primary peritoneal sarcomas have been reported as leiomyosarcoma, liposarcoma and carcinosarcoma. However, primary peritoneal spindle cell sarcoma has never been reported in the literature. Herein, we report on a 38-year-old woman with massive ascites diagnosed as primary peritoneal spindle cell sarcoma. Following doxorubicin and ifosfamide chemotherapy, her symptoms improved and ascites regressed. Other primary peritoneal sarcomas rarely cause massive ascites. We suggest that in patients presenting with massive exudative ascites associated with malignancy, primary peritoneal sarcomas should be also considered in the differential diagnosis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Ascites / drug therapy
  • Ascites / etiology*
  • Ascites / pathology
  • Doxorubicin / administration & dosage
  • Female
  • Humans
  • Ifosfamide / administration & dosage
  • Peritoneal Neoplasms / complications*
  • Peritoneal Neoplasms / diagnosis
  • Peritoneal Neoplasms / drug therapy
  • Prognosis
  • Sarcoma / complications*
  • Sarcoma / diagnosis
  • Sarcoma / drug therapy
  • Soft Tissue Neoplasms / complications*
  • Soft Tissue Neoplasms / diagnosis
  • Soft Tissue Neoplasms / drug therapy
  • Treatment Outcome

Substances

  • Doxorubicin
  • Ifosfamide