Abstract
Bambuterol, a carbamate prodrug of terbutaline as a 5, 10, or 20-mg tablet, was given once every evening to patients with asthma in a randomized double-blind crossover study. Twenty milligrams improved pulmonary functions over 24 hours; 5 and 10 mg did not. Few side effects were observed.
Publication types
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Clinical Trial
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Randomized Controlled Trial
MeSH terms
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Administration, Oral
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Adolescent
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Adult
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Aged
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Asthma / drug therapy*
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Bronchi / drug effects
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Bronchi / physiology
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Bronchodilator Agents / administration & dosage
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Bronchodilator Agents / adverse effects
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Bronchodilator Agents / therapeutic use*
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Circadian Rhythm / physiology
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Dose-Response Relationship, Drug
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Double-Blind Method
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Female
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Humans
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Male
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Middle Aged
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Terbutaline / administration & dosage
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Terbutaline / adverse effects
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Terbutaline / analogs & derivatives*
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Terbutaline / therapeutic use
Substances
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Bronchodilator Agents
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Terbutaline
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bambuterol