Perinatal clinical and imaging features of CLOVES syndrome

Pediatr Radiol. 2010 Aug;40(8):1436-9. doi: 10.1007/s00247-010-1559-0. Epub 2010 Feb 13.


We report a neonate with antenatal imaging features suggestive of CLOVES syndrome. Postnatal clinical and imaging findings confirmed the diagnosis, with the constellation of truncal overgrowth, cutaneous capillary malformation, lymphatic and musculoskeletal anomalies. The clinical, radiological and histopathological findings noted in this particular phenotype help differentiate it from other overgrowth syndromes with complex vascular anomalies.

Publication types

  • Case Reports

MeSH terms

  • Abnormalities, Multiple / diagnostic imaging*
  • Facial Asymmetry / complications
  • Humans
  • Infant, Newborn*
  • Musculoskeletal Abnormalities / complications
  • Musculoskeletal Abnormalities / diagnostic imaging*
  • Port-Wine Stain / complications
  • Radiography
  • Syndrome
  • Vascular Malformations / complications
  • Vascular Malformations / diagnostic imaging*