Abstract
The nematode Caenorhabditis elegans is a favorite model for the study of aging. A wealth of genetic and genomic studies show that metabolic regulation is a hallmark of life-span modulation. A recent study in BMC Biology identifying metabolic signatures for longevity suggests that amino-acid pools may be important in longevity.
MeSH terms
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Adenosine Triphosphate / metabolism*
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Aging / genetics
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Aging / metabolism
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Animals
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Caenorhabditis elegans / metabolism*
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Caenorhabditis elegans Proteins / metabolism*
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Cell Differentiation / physiology
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Energy Metabolism / physiology*
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Gene Expression Regulation, Developmental
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Genes, Helminth / physiology
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Life Expectancy
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Lipid Metabolism / physiology
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Longevity / genetics
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Longevity / physiology*
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Models, Animal
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Mutation
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Oxidative Stress / genetics
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Oxidative Stress / physiology
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Promoter Regions, Genetic / physiology
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Signal Transduction / physiology*
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Temperature
Substances
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Caenorhabditis elegans Proteins
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Adenosine Triphosphate