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Review
. 2010 Mar;8(3):207-17.
doi: 10.1038/nrmicro2298.

The Population Genetics of Commensal Escherichia Coli

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Review

The Population Genetics of Commensal Escherichia Coli

Olivier Tenaillon et al. Nat Rev Microbiol. .

Abstract

The primary habitat of Escherichia coli is the vertebrate gut, where it is the predominant aerobic organism, living in symbiosis with its host. Despite the occurrence of recombination events, the population structure is predominantly clonal, allowing the delineation of major phylogenetic groups. The genetic structure of commensal E. coli is shaped by multiple host and environmental factors, and the determinants involved in the virulence of the bacteria may in fact reflect adaptation to commensal habitats. A better characterization of the commensal niche is necessary to understand how a useful commensal can become a harmful pathogen. In this Review we describe the population structure of commensal E. coli, the factors involved in the spread of different strains, how the bacteria can adapt to different niches and how a commensal lifestyle can evolve into a pathogenic one.

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References

    1. Infect Immun. 1983 Feb;39(2):686-703 - PubMed
    1. Appl Environ Microbiol. 2000 Jan;66(1):230-7 - PubMed
    1. Genetics. 1990 Nov;126(3):505-17 - PubMed
    1. Nature. 2000 May 18;405(6784):299-304 - PubMed
    1. Vet Microbiol. 2008 Sep 18;131(1-2):173-84 - PubMed

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