[Presurgical functional magnetic resonance imaging]

Radiologe. 2010 Feb;50(2):110-22. doi: 10.1007/s00117-009-1893-0.
[Article in German]

Abstract

Functional magnetic resonance imaging (fMRI) is an important and novel neuroimaging modality for patients with brain tumors. By non-invasive measurement, localization and lateralization of brain activiation, most importantly of motor and speech function, fMRI facilitates the selection of the most appropriate and sparing treatment and function-preserving surgery. Prerequisites for the diagnostic use of fMRI are the application of dedicated clinical imaging protocols and standardization of the respective imaging procedures. The combination with diffusion tensor imaging (DTI) also enables tracking and visualization of important fiber bundles such as the pyramidal tract and the arcuate fascicle. These multimodal MR data can be implemented in computer systems for functional neuronavigation or radiation treatment. The practicability, accuracy and reliability of presurgical fMRI have been validated by large numbers of published data. However, fMRI cannot be considered as a fully established modality of diagnostic neuroimaging due to the lack of guidelines of the responsible medical associations as well as the lack of medical certification of important hardware and software components. This article reviews the current research in the field and provides practical information relevant for presurgical fMRI.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Afferent Pathways / physiopathology
  • Afferent Pathways / surgery
  • Artifacts
  • Brain Mapping / instrumentation
  • Brain Mapping / methods*
  • Brain Neoplasms / physiopathology*
  • Brain Neoplasms / surgery*
  • Cerebral Cortex / physiopathology*
  • Cerebral Cortex / surgery*
  • Diffusion Magnetic Resonance Imaging / instrumentation
  • Diffusion Magnetic Resonance Imaging / methods*
  • Dominance, Cerebral / physiology
  • Electric Stimulation / instrumentation
  • Electric Stimulation / methods
  • Humans
  • Image Processing, Computer-Assisted / instrumentation
  • Image Processing, Computer-Assisted / methods*
  • Imaging, Three-Dimensional / instrumentation
  • Imaging, Three-Dimensional / methods*
  • Magnetic Resonance Imaging / instrumentation
  • Magnetic Resonance Imaging / methods*
  • Motor Activity / physiology
  • Motor Cortex / physiopathology
  • Motor Cortex / surgery
  • Nerve Fibers / physiology
  • Neural Pathways / physiopathology
  • Neuronal Plasticity / physiology
  • Neuronavigation / instrumentation
  • Neuronavigation / methods
  • Oxygen / blood*
  • Preoperative Care
  • Software
  • Somatosensory Cortex / physiopathology
  • Somatosensory Cortex / surgery
  • Speech / physiology

Substances

  • Oxygen