A Contingency-Management Intervention to Promote Initial Smoking Cessation Among Opioid-Maintained Patients

Exp Clin Psychopharmacol. 2010 Feb;18(1):37-50. doi: 10.1037/a0018649.

Abstract

Prevalence of cigarette smoking among opioid-maintained patients is more than threefold that of the general population and associated with increased morbidity and mortality. Relatively few studies have evaluated smoking interventions in this population. The purpose of the present study was to examine the efficacy of contingency management for promoting initial smoking abstinence. Forty methadone- or buprenorphine-maintained cigarette smokers were randomly assigned to a contingent (n = 20) or noncontingent (n = 20) experimental group and visited the clinic for 14 consecutive days. Contingent participants received vouchers based on breath carbon monoxide levels during Study Days 1 to 5 and urinary cotinine levels during Days 6 to 14. Voucher earnings began at $9.00 and increased by $1.50 with each subsequent negative sample for maximum possible of $362.50. Noncontingent participants earned vouchers independent of smoking status. Although not a primary focus, participants who were interested and medically eligible could also receive bupropion (Zyban). Contingent participants achieved significantly more initial smoking abstinence, as evidenced by a greater percentage of smoking-negative samples (55% vs. 17%) and longer duration of continuous abstinence (7.7 vs. 2.4 days) during the 2 week quit attempt than noncontingent participants, respectively. Bupropion did not significantly influence abstinence outcomes. Results from this randomized clinical trial support the efficacy of contingency management interventions in promoting initial smoking abstinence in this challenging population.

Publication types

  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Analgesics, Opioid / administration & dosage*
  • Behavior Therapy* / methods
  • Bupropion / administration & dosage
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Smoking / drug therapy*
  • Smoking / psychology*
  • Smoking / therapy
  • Smoking Cessation / methods
  • Smoking Cessation / psychology*
  • Time Factors
  • Treatment Outcome

Substances

  • Analgesics, Opioid
  • Bupropion