Abstract
In this issue of Structure, Kitano et al. describe the structure of the DNA-bound winged-helix domain from the Werner helicase. This structure of a RecQ/DNA complex offers insights into the DNA-unwinding mechanisms of RecQ family helicases.
Copyright 2010 Elsevier Inc. All rights reserved.
MeSH terms
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DNA* / chemistry
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DNA* / metabolism
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Exodeoxyribonucleases / chemistry*
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Exodeoxyribonucleases / genetics
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Exodeoxyribonucleases / metabolism*
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Humans
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Isoenzymes / chemistry
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Isoenzymes / genetics
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Isoenzymes / metabolism
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Models, Molecular
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Protein Structure, Tertiary
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RecQ Helicases / chemistry*
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RecQ Helicases / genetics
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RecQ Helicases / metabolism*
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Werner Syndrome / enzymology*
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Werner Syndrome Helicase
Substances
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Isoenzymes
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DNA
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Exodeoxyribonucleases
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RecQ Helicases
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WRN protein, human
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Werner Syndrome Helicase