The epidemiology of germinal matrix hemorrhage during the first half-day of life

Dev Med Child Neurol. 1991 Feb;33(2):138-45. doi: 10.1111/j.1469-8749.1991.tb05092.x.


The personal and maternal characteristics of 27 babies with early-onset germinal matrix hemorrhage (EGMH) were compared with those of 280 babies with normal cranial ultrasonograms, studied in a separate clinical trial. None of the mothers of the babies with EGMH had high blood pressure or pre-eclampsia during pregnancy. Gestational age less than 30 weeks and initial pH less than 7.2 indicated increased risks of EGMH, and maternal receipt of steroids indicated reduced risk of EGMH. Thus prenatal and immediately perinatal factors appear to convey much of the information about the risk of EGMH.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Cerebral Hemorrhage / diagnostic imaging
  • Cerebral Hemorrhage / epidemiology*
  • Cerebral Hemorrhage / prevention & control
  • Cerebral Ventricles / diagnostic imaging
  • Cross-Sectional Studies
  • Echoencephalography
  • Ependyma / diagnostic imaging
  • Humans
  • Incidence
  • Infant, Newborn
  • Infant, Premature, Diseases / diagnostic imaging
  • Infant, Premature, Diseases / epidemiology*
  • Infant, Premature, Diseases / prevention & control
  • Massachusetts / epidemiology
  • Phenobarbital / administration & dosage


  • Phenobarbital