Loss of PTEN expression predicts resistance to EGFR-targeted monoclonal antibodies in patients with metastatic colorectal cancer

Br J Cancer. 2010 Mar 2;102(5):940. doi: 10.1038/sj.bjc.6605575. Epub 2010 Feb 16.
No abstract available

Publication types

  • Letter

MeSH terms

  • Antibodies, Monoclonal / pharmacology*
  • Colorectal Neoplasms / immunology
  • Colorectal Neoplasms / secondary*
  • Colorectal Neoplasms / therapy*
  • ErbB Receptors / antagonists & inhibitors
  • ErbB Receptors / immunology*
  • ErbB Receptors / metabolism
  • Humans
  • Meta-Analysis as Topic
  • PTEN Phosphohydrolase / deficiency*
  • Prognosis

Substances

  • Antibodies, Monoclonal
  • EGFR protein, human
  • ErbB Receptors
  • PTEN Phosphohydrolase
  • PTEN protein, human