A new abietic acid-type diterpene glucoside from the needles of Pinus densiflora

Arch Pharm Res. 2009 Dec;32(12):1699-704. doi: 10.1007/s12272-009-2206-x. Epub 2010 Feb 17.

Abstract

From the ethyl acetate fraction of the methanol extract of the needles of Pinus densiflora (Pinaceae), a new diterpenoid glucoside [9alpha,13alpha-epoxy-8beta,14beta-dihydroxy-abietic acid-18-O-beta-D: -glucopyranoside] (1), two flavonoid glucosides [kaempferol 3-O-beta-D: -glucoside (2) and 6-C-methyl kaempferol 3-O-beta-D: -glucoside (3)], and two monoterpenoid glucosides [bornyl 6-O-alpha-Larabinofuranosyl (1-->6)-beta-D: -glucopyranoside (4) and bornyl 6-O-beta-D: -apiofuranosyl (1-->6)-beta-D: -glucopyranoside (5)] were isolated and characterized on the basis of spectral analysis. Of all the compounds, 2 and 3 showed peroxynitrite scavenging activity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abietanes / chemistry*
  • Abietanes / isolation & purification
  • Carbohydrates / chemistry
  • Chromatography, High Pressure Liquid
  • Flavonoids / chemistry
  • Flavonoids / isolation & purification
  • Free Radical Scavengers / chemistry*
  • Free Radical Scavengers / isolation & purification
  • Free Radicals / chemistry
  • Glucosides / chemistry*
  • Glucosides / isolation & purification
  • Glycosides / chemistry
  • Glycosides / isolation & purification
  • Indicators and Reagents
  • Magnetic Resonance Spectroscopy
  • Peroxynitrous Acid / chemistry
  • Pinus / chemistry*
  • Plant Extracts / chemistry
  • Plant Leaves / chemistry
  • Spectrometry, Mass, Fast Atom Bombardment

Substances

  • 9,13-epoxy-8,14-dihydroxyabietic acid-18-O-glucopyranoside
  • Abietanes
  • Carbohydrates
  • Flavonoids
  • Free Radical Scavengers
  • Free Radicals
  • Glucosides
  • Glycosides
  • Indicators and Reagents
  • Plant Extracts
  • Peroxynitrous Acid
  • abietic acid