Radiation dose-volume effects in the lung

Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3 Suppl):S70-6. doi: 10.1016/j.ijrobp.2009.06.091.


The three-dimensional dose, volume, and outcome data for lung are reviewed in detail. The rate of symptomatic pneumonitis is related to many dosimetric parameters, and there are no evident threshold "tolerance dose-volume" levels. There are strong volume and fractionation effects.

Publication types

  • Meta-Analysis
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Humans
  • Lung / radiation effects*
  • Lung Neoplasms / pathology
  • Lung Neoplasms / radiotherapy
  • Models, Biological
  • Models, Statistical
  • Radiation Pneumonitis / etiology*
  • Radiation Tolerance
  • Radiotherapy Dosage