Francisella tularensis is a zoonotic infection that can be acquired in multiple ways, including a bite from an arthropod, the handling of animal carcasses, consumption of contaminated food and water, or inhalation of infected particles. The most virulent subspecies of F tularensis is type A, which is almost exclusively seen in North America. Pneumonia can occur in tularemia, as either a primary process from direct inhalation, or as a secondary manifestation of ulceroglandular or typhoidal disease. This article describes the history of this infection, epidemiology, methods of diagnosis and treatment, and its potential as a bioterrorism weapon.
Published by Elsevier Inc.