Improvement of restless legs syndrome and trichotillomania with aripiprazole

J Clin Pharm Ther. 2009 Dec;34(6):723-5. doi: 10.1111/j.1365-2710.2009.01051.x.


The case report describes a 39-year-old woman with restless legs syndrome (RLS) and trichotillomania (TTM). She was treated with venlafaxine and clonazepam with partial remission of RLS and no response for TTM. When aripiprazole was added to the clonazepam both RLS and TTM fully remitted. We suggest that aripiprazole might be worth investigating for treatment of these disorders.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antipsychotic Agents / therapeutic use*
  • Aripiprazole
  • Female
  • Humans
  • Piperazines / therapeutic use*
  • Quinolones / therapeutic use*
  • Restless Legs Syndrome / drug therapy*
  • Trichotillomania / drug therapy*


  • Antipsychotic Agents
  • Piperazines
  • Quinolones
  • Aripiprazole