The genetics of ischaemic stroke

J Intern Med. 2010 Feb;267(2):139-55. doi: 10.1111/j.1365-2796.2009.02202.x.


In this review, we discuss the genetic factors in both the aetiology and treatment of ischaemic stroke. We discuss candidate gene association studies, family linkage studies and the more recent whole genome association studies and whole genome expression studies. We also briefly discuss genetic testing for stroke risk and genetic analysis of treatment complications.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Brain Ischemia / genetics*
  • Brain Ischemia / therapy
  • Genetic Linkage
  • Genetic Predisposition to Disease
  • Humans
  • Polymorphism, Single Nucleotide / genetics
  • Risk Factors
  • Stroke / genetics*
  • Stroke / therapy