Nutrition and the brain

Clin Geriatr Med. 2010 Feb;26(1):89-98. doi: 10.1016/j.cger.2009.11.005.


Severe nutritional deficiencies, such as protein energy malnutrition and deficiency of nicotinamide, vitamin B(12), folate, and thiamine, have long been recognized to cause severe confusion. Lesser vitamin deficiencies have been linked to the pathogenesis of delirium. Hypo- and hyperglycemia and hypertriglyceridemia can cause cognitive deficits. Epidemiologic and animal studies have linked several other nutrients (omega-3 fatty acids, lutein, alpha-lipoic acid, and the Mediterranean diet) to cognitive performance and the prevention of dementia.

Publication types

  • Review

MeSH terms

  • Appetite Regulation / physiology*
  • Cognition Disorders / etiology*
  • Cognition Disorders / metabolism
  • Cognition Disorders / prevention & control
  • Dementia / etiology*
  • Dementia / metabolism
  • Dementia / prevention & control
  • Humans
  • Nutrition Disorders / metabolism
  • Nutrition Disorders / psychology*
  • Nutrition Disorders / therapy