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Review
. 2010 Feb 15;16(2):3.

Does D Matter? The Role of Vitamin D in Hair Disorders and Hair Follicle Cycling

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  • PMID: 20178699
Free article
Review

Does D Matter? The Role of Vitamin D in Hair Disorders and Hair Follicle Cycling

Karrie T Amor et al. Dermatol Online J. .
Free article

Abstract

Background: The role of vitamin D in the proliferation and differentiation of keratinocytes is well known within the field of dermatology.

Objective: We sought to evaluate the role that vitamin D and the vitamin D receptor play in the hair cycle and assess how this can be clinically applied to the treatment of hair disorders.

Methods: A MEDLINE search (1955-July 2009) was preformed to find relevant articles pertaining to vitamin D, the vitamin D receptor, and hair loss.

Results: The vitamin D receptor, independent of vitamin D, plays an important role in hair cycling, specifically anagen initiation. The role of vitamin D in hair follicle cycling is not as well understood.

Limitations: The review is broad and there are limited human studies available to date.

Conclusion: Additional studies to evaluate the role of vitamin D in the hair cycle should be done. Treatments that up regulate the vitamin D receptor may be successful in treating hair disorders and are a potential area of further study.

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