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, 140 (4), 445-9

Lin28: A microRNA Regulator With a Macro Role

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Lin28: A microRNA Regulator With a Macro Role

Srinivas R Viswanathan et al. Cell.

Abstract

Lin28, a highly conserved RNA-binding protein, has emerged as a modulator of the processing of the let-7 microRNA. This role for Lin28 has important implications for our mechanistic understanding of pluripotency, the timing of development, and oncogenesis.

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