Abstract
High-resolution crystal structures of DNA complexes with the bacterial MutM protein show how the enzyme feels its way around the double helix in search of an oxidized guanine before flipping it out into its active site and excising it.
Copyright 2010 Elsevier Ltd. All rights reserved.
MeSH terms
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DNA / metabolism*
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DNA Repair / physiology*
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DNA-Formamidopyrimidine Glycosylase / metabolism*
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Escherichia coli Proteins / metabolism*
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Macromolecular Substances / metabolism*
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Models, Genetic*
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Nucleic Acid Conformation
Substances
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Escherichia coli Proteins
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Macromolecular Substances
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DNA
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DNA-Formamidopyrimidine Glycosylase
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DNA-formamidopyrimidine glycosylase, E coli