Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia

Leukemia. 2010 May;24(5):1062-5. doi: 10.1038/leu.2010.20. Epub 2010 Feb 25.
No abstract available

Publication types

  • Comparative Study
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomarkers, Tumor / genetics*
  • Biomarkers, Tumor / metabolism
  • Case-Control Studies
  • Gene Expression Profiling
  • Genotype
  • Humans
  • Leukemia, Myeloid, Acute / genetics*
  • Leukemia, Myeloid, Acute / pathology
  • Leukemia, Myelomonocytic, Chronic / genetics*
  • Leukemia, Myelomonocytic, Chronic / pathology
  • Mutation / genetics*
  • Myelodysplastic Syndromes / genetics*
  • Myelodysplastic Syndromes / pathology
  • Oligonucleotide Array Sequence Analysis
  • Polymorphism, Single Nucleotide
  • Repressor Proteins / genetics*

Substances

  • ASXL1 protein, human
  • Biomarkers, Tumor
  • Repressor Proteins