Is idiopathic intracranial hypertension without papilledema a risk factor for migraine progression?

Neurol Sci. 2010 Aug;31(4):411-5. doi: 10.1007/s10072-010-0229-1. Epub 2010 Feb 25.


The association of chronic migraine (CM) with an idiopathic intracranial hypertension without papilledema (IIHWOP), although much more prevalent than expected in clinical series of CM sufferers, is not included among the risk factors for migraine progression. We discuss the available evidence supporting the existence of a pathogenetic link between CM and idiopathic intracranial hypertensive disorders and suggest a causative role for IIHWOP in migraine progression.

Publication types

  • Review

MeSH terms

  • Disease Progression
  • Female
  • Humans
  • Migraine Disorders / complications*
  • Migraine Disorders / epidemiology
  • Migraine Disorders / genetics
  • Migraine Disorders / physiopathology*
  • Papilledema / complications*
  • Papilledema / genetics
  • Pseudotumor Cerebri / complications*
  • Pseudotumor Cerebri / genetics
  • Risk Factors