A pilot study to assess the efficacy of biofeedback-assisted relaxation training as an adjunct treatment for pediatric functional dyspepsia associated with duodenal eosinophilia

J Pediatr Psychol. 2010 Sep;35(8):837-47. doi: 10.1093/jpepsy/jsq010. Epub 2010 Feb 25.


Objectives: To conduct a pilot study examining whether adding biofeedback-assisted relaxation training (BART) to medication treatment results in better clinical outcomes than medication treatment alone for children with functional dyspepsia (FD) associated with duodenal eosinophilia, a subgroup of children with recurrent abdominal pain.

Methods: Twenty children were randomly assigned to receive a standardized medication treatment or medication plus 10 sessions of BART. Children and parents completed psychosocial functioning and quality of life measures at baseline, posttreatment, and 6 months. Children rated pain daily via PDA. Physicians provided biweekly assessments of clinical improvement.

Results: Children receiving medication plus BART demonstrated better outcomes on pain intensity, duration of pain episodes, and clinical improvement than children receiving medication alone.

Conclusions: BART is a promising adjunctive treatment for pediatric FD associated with duodenal eosinophilia. Electronic daily diaries appear to be a useful approach to assessing changes in self-reported pain ratings in this population.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abdominal Pain / therapy
  • Adolescent
  • Analysis of Variance
  • Biofeedback, Psychology / methods*
  • Child
  • Combined Modality Therapy
  • Duodenal Diseases / complications
  • Duodenal Diseases / therapy*
  • Dyspepsia / complications
  • Dyspepsia / therapy*
  • Eosinophilia / complications
  • Eosinophilia / therapy*
  • Female
  • Humans
  • Male
  • Pain Measurement
  • Pilot Projects
  • Quality of Life
  • Relaxation Therapy / methods*
  • Surveys and Questionnaires
  • Treatment Outcome