Genomic responses to abnormal gene dosage: the X chromosome improved on a common strategy

PLoS Biol. 2010 Feb 23;8(2):e1000318. doi: 10.1371/journal.pbio.1000318.


This new primer, which discusses a study by Zhang et al., provides an overview of the process by which chromosomes achieve dose compensation and the mechanisms underlying this phenomenon in Drosophila S2 cells.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Aneuploidy
  • Animals
  • Gene Dosage / genetics*
  • Humans
  • X Chromosome / genetics*