Technical note: Assessment of blinding of hand hygiene observers in randomized controlled trials of hand hygiene interventions

Am J Infect Control. 2010 May;38(4):332-4. doi: 10.1016/j.ajic.2009.10.005. Epub 2010 Mar 1.


Trials evaluating interventions to improve health care workers' hand hygiene compliance use directly observed compliance as a primary outcome measure. Observers should be blinded to the intervention and the effectiveness of blinding assessed to prevent systematic bias. The literature has not addressed this issue, and this study describes a robust and pragmatic method for assessing the adequacy of blinding in hand hygiene intervention trials.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomedical Research / methods*
  • Cross Infection / prevention & control
  • Guideline Adherence / statistics & numerical data*
  • Hand Disinfection*
  • Health Personnel
  • Humans
  • Infection Control / methods*
  • Randomized Controlled Trials as Topic*