Abstract
An improved synthesis of 5-amino-1,2-dihydrofuro[2,3-c]isoquinoline has been achieved using a slight modification of reaction conditions for the Truce-Smiles rearrangement. Acid treatment of the obtained 5-amino-1,2-dihydrofuro[2,3-c]isoquinolines gave unexpected ring-opened spiro ring compounds. The previously unreported parent compound, furo[2,3-c]isoquinoline, was also synthesized.
MeSH terms
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Heterocyclic Compounds / chemical synthesis*
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Heterocyclic Compounds / chemistry
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Isoquinolines / chemical synthesis*
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Isoquinolines / chemistry
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Molecular Structure
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Polycyclic Compounds / chemical synthesis*
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Polycyclic Compounds / chemistry
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Stereoisomerism
Substances
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5-amino-1,2-dihydrofuro(2,3-c)isoquinoline
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Heterocyclic Compounds
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Isoquinolines
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Polycyclic Compounds
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furo(2,3-c)isoquinoline