Omega-3 fatty acids and blood pressure

Cell Mol Biol (Noisy-le-grand). 2010 Feb 25;56(1):83-92.


There is substantial evidence that omega-3 fatty acids reduce blood pressure, with a greater effect in hypertensive patients and those with high-normal blood pressure. The dose of omega-3 fatty acids required to achieve a blood pressure reduction is likely to be at least 3-4 g/day. However, the magnitude of the blood pressure change can be increased by salt restriction or when omega-3 fatty acids are incorporated into a weight reducing program. It is also highly plausible that increased omega-3 fatty acid consumption as part of a dietary change including increased consumption of fruits and vegetables, and moderation of salt intake, will confer significant cardiovascular benefit.

MeSH terms

  • Animals
  • Antihypertensive Agents / pharmacology*
  • Blood Pressure / drug effects*
  • Catecholamines / physiology
  • Controlled Clinical Trials as Topic
  • Endothelium / drug effects
  • Fatty Acids, Omega-3 / pharmacology*
  • Female
  • Humans
  • Meta-Analysis as Topic
  • Population Surveillance
  • Rats
  • Vasodilation / drug effects


  • Antihypertensive Agents
  • Catecholamines
  • Fatty Acids, Omega-3