Guidelines for the labelling of leucocytes with (99m)Tc-HMPAO. Inflammation/Infection Taskgroup of the European Association of Nuclear Medicine

Eur J Nucl Med Mol Imaging. 2010 Apr;37(4):842-8. doi: 10.1007/s00259-010-1394-4.


We describe here a protocol for labelling autologous white blood cells with (99m)Tc-HMPAO based on previously published consensus papers and guidelines. This protocol includes quality control and safety procedures and is in accordance with current European Union regulations and International Atomic Energy Agency recommendations.

Publication types

  • Practice Guideline

MeSH terms

  • Cell Separation / methods
  • Chemotaxis, Leukocyte
  • Humans
  • Infections / diagnostic imaging
  • Inflammation / diagnostic imaging
  • Isotope Labeling / methods*
  • Leukocytes*
  • Quality Control
  • Radiation Protection / legislation & jurisprudence
  • Radiation Protection / methods
  • Radionuclide Imaging
  • Radiopharmaceuticals* / pharmacokinetics
  • Technetium Tc 99m Exametazime* / pharmacokinetics
  • Tissue Distribution


  • Radiopharmaceuticals
  • Technetium Tc 99m Exametazime