Cancer and Inflammation: Implications for Pharmacology and Therapeutics

Clin Pharmacol Ther. 2010 Apr;87(4):401-6. doi: 10.1038/clpt.2009.312. Epub 2010 Mar 3.

Abstract

Smoldering, nonresolving inflammation is a component of the tumor microenvironment. The linkage between inflammation and cancer, first perceived in the nineteenth century, is now part of an accepted paradigm of carcinogenesis.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Inflammatory Agents / pharmacology
  • Clinical Trials as Topic
  • Cytokines / metabolism
  • Drug Delivery Systems*
  • Drug Evaluation, Preclinical
  • Humans
  • Inflammation / complications*
  • Inflammation / drug therapy
  • Inflammation / physiopathology
  • Neoplasms / etiology*
  • Neoplasms / physiopathology
  • Neoplasms / prevention & control

Substances

  • Anti-Inflammatory Agents
  • Cytokines