Involvement of L-carnitine in cellular metabolism: beyond Acyl-CoA transport

Mini Rev Med Chem. 2009 Nov 1;9(13):1518-26. doi: 10.2174/138955709790361502.

Abstract

Carnitine is well-known for its role in the transport of fatty acids to the mitochondrial matrix, where beta-oxidation takes place. This work describes novel functions for this compound and novel data on its pharmacokinetics.

Publication types

  • Review

MeSH terms

  • Acetylation
  • Acyl Coenzyme A / metabolism*
  • Animals
  • Apoptosis
  • Biological Transport
  • Carnitine / metabolism*
  • Carnitine / pharmacokinetics
  • Humans
  • Organic Cation Transport Proteins / genetics
  • Organic Cation Transport Proteins / physiology
  • Solute Carrier Family 22 Member 5

Substances

  • Acyl Coenzyme A
  • Organic Cation Transport Proteins
  • SLC22A5 protein, human
  • Solute Carrier Family 22 Member 5
  • Carnitine