Canine morphology: hunting for genes and tracking mutations

PLoS Biol. 2010 Mar 2;8(3):e1000310. doi: 10.1371/journal.pbio.1000310.


In this essay, Abigail Shearin and Elaine Ostrander discuss the proposed genomic mechanisms for the extraordinary level of phenotypic variation observed in the domestic dog and the evidence detailing the variants responsible for the many shapes, sizes, textures, and colors of man's best friend.

Publication types

  • Research Support, N.I.H., Intramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Breeding
  • Dogs* / anatomy & histology
  • Dogs* / genetics
  • Genetic Variation*
  • Genome
  • Genotype
  • Linkage Disequilibrium
  • Mutation*
  • Phenotype