Effects of cigarette smoking on the respiratory epithelium and its role in the pathogenesis of chronic rhinosinusitis

Braz J Otorhinolaryngol. Nov-Dec 2009;75(6):903-7. doi: 10.1016/s1808-8694(15)30557-7.

Abstract

The increasing consumption of cigarettes has aroused concerns about the development and worsening of diseases, particularly those related to the respiratory tract.

Aim: In this paper we review the evidence suggesting the effects of cigarette smoking on the respiratory epithelium and its role in the pathogenesis in chronic rhinosinusitis.

Conclusions: Although there is evidence supporting a link between smoking and CRS, studies suggest that there might be individual susceptibility to cigarette smoking causing the development and/or maintenance of CRS. Proper patient education to quit smoking as well as reinforcement of antismoking campaigns are extremely important to control this disease of major socio-economic impact.

Publication types

  • Review

MeSH terms

  • Chronic Disease
  • Humans
  • Microscopy, Electron, Scanning
  • Respiratory Mucosa* / ultrastructure
  • Rhinitis / etiology*
  • Sinusitis / etiology*
  • Smoking / adverse effects*