Enhanced fluorescence of curcumin on plasmonic platforms

Curr Pharm Biotechnol. 2010 Feb;11(2):223-8. doi: 10.2174/138920110790909623.


We report a significant increase of a curcumin (1,7-bis[4-hydroxy-3-methoxyphenyl]-1,6-heptadiene-3,5-dione) fluorescence brightness when deposited on plasmonic platforms (self assembled silver nanostructures formed on the surface of silver semitransparent film). The enhancement of fluorescence intensity is accompanied by a strong decrease in fluorescence lifetime. Simultaneously, the increased photostability of curcumin, a pigment showing strong anti-inflammatory, antioxidant and antitumorigenic activity, allows long-time detection and monitoring. We believe that the use of plasmonic platforms will improve detection, delivery and imaging of curcumin.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Curcumin / analysis*
  • Curcumin / chemistry
  • Fluorescence*
  • Glass
  • Microscopy, Atomic Force
  • Microscopy, Fluorescence
  • Molecular Structure
  • Nanostructures / chemistry*
  • Photochemical Processes
  • Polyvinyl Alcohol / chemistry
  • Silver / chemistry*
  • Spectrometry, Fluorescence
  • Surface Plasmon Resonance / instrumentation
  • Surface Plasmon Resonance / methods*


  • Silver
  • Polyvinyl Alcohol
  • Curcumin