What is flux balance analysis?

Nat Biotechnol. 2010 Mar;28(3):245-8. doi: 10.1038/nbt.1614.


Flux balance analysis is a mathematical approach for analyzing the flow of metabolites through a metabolic network. This primer covers the theoretical basis of the approach, several practical examples and a software toolbox for performing the calculations.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Biomass
  • Escherichia coli / metabolism
  • Metabolic Networks and Pathways*
  • Models, Biological*
  • Oxygen / metabolism
  • Phenotype
  • Systems Biology / methods*


  • Oxygen