Effect of Incarceration History on Outcomes of Primary Care Office-Based buprenorphine/naloxone

J Gen Intern Med. 2010 Jul;25(7):670-4. doi: 10.1007/s11606-010-1306-0. Epub 2010 Mar 6.

Abstract

Background: Behaviors associated with opioid dependence often involve criminal activity, which can lead to incarceration. The impact of a history of incarceration on outcomes in primary care office-based buprenorphine/naloxone is not known.

Objective: The purpose of this study is to determine whether having a history of incarceration affects response to primary care office-based buprenorphine/naloxone treatment.

Design: In this post hoc secondary analysis of a randomized clinical trial, we compared demographic, clinical characteristics, and treatment outcomes among 166 participants receiving primary care office-based buprenorphine/naloxone treatment stratifying on history of incarceration.

Main results: Participants with a history of incarceration have similar treatment outcomes with primary care office-based buprenorphine/naloxone than those without a history of incarceration (consecutive weeks of opioid-negative urine samples, 6.2 vs. 5.9, p = 0.43; treatment retention, 38% vs. 46%, p = 0.28).

Conclusions: Prior history of incarceration does not appear to impact primary care office-based treatment of opioid dependence with buprenorphine/naloxone. Community health care providers can be reassured that initiating buprenorphine/naloxone in opioid dependent individuals with a history of incarceration will have similar outcomes as those without this history.

Publication types

  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Buprenorphine / administration & dosage*
  • Criminals / psychology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Naloxone / administration & dosage*
  • Office Visits*
  • Opioid-Related Disorders / drug therapy
  • Opioid-Related Disorders / psychology*
  • Primary Health Care* / methods
  • Socioeconomic Factors
  • Treatment Outcome
  • Young Adult

Substances

  • Naloxone
  • Buprenorphine