Abstract
Imiquimod has immune-stimulant properties that can precipitate autoimmune conditions like eczema, psoriasis and lichenoid conditions. We report two cases here where imiquimod induced florid lichen sclerosus in one patient and lichen planus in another. In both patients the condition was so aggressive and unresponsive to steroid treatment that circumcision was necessary.
MeSH terms
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Adjuvants, Immunologic / adverse effects*
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Adjuvants, Immunologic / therapeutic use
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Adult
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Aminoquinolines / adverse effects*
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Aminoquinolines / therapeutic use
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Circumcision, Male
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Condylomata Acuminata / drug therapy*
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Humans
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Imiquimod
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Lichen Planus / diagnosis*
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Lichen Planus / immunology
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Lichen Planus / surgery
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Lichen Sclerosus et Atrophicus / diagnosis*
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Lichen Sclerosus et Atrophicus / immunology
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Lichen Sclerosus et Atrophicus / surgery
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Male
Substances
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Adjuvants, Immunologic
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Aminoquinolines
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Imiquimod