[Physical activity and peripheral arterial obstructive disease]

Rev Med Suisse. 2010 Feb 10;6(235):278-81.
[Article in French]


Intermittent claudication (IC) is the most common clinical manifestation of atherosclerotic peripheral arterial disease. Exercise training plays a major role in treating patients with IC. Regular exercise increases functional walking capacity, reduces cardiovascular mortality and improves quality of life. This seems to be achieved by: favorable effect on cardiovascular risk factors, anti-inflammatory effect, increased collateral blood flux, improved rheology profile, endothelial function, fibrinolysis, and muscular metabolism. However, exact mechanisms underlying beneficial effect of exercise remain largely unknown. Exercise modalities will be discussed in this article.

Publication types

  • English Abstract

MeSH terms

  • Arterial Occlusive Diseases / classification
  • Arterial Occlusive Diseases / rehabilitation*
  • Arteriosclerosis Obliterans / rehabilitation
  • Exercise*
  • Fibrinolysis / physiology
  • Hemorheology / physiology
  • Humans
  • Inflammation / prevention & control
  • Intermittent Claudication / classification
  • Intermittent Claudication / rehabilitation
  • Leg / blood supply*
  • Peripheral Vascular Diseases / classification
  • Peripheral Vascular Diseases / rehabilitation*
  • Walking