Patency rate and complications of polytetrafluoroethylene grafts compared with polyurethane grafts for hemodialysis access

Ups J Med Sci. 2010 Nov;115(4):245-8. doi: 10.3109/03009731003678562. Epub 2010 Mar 11.


Background: The survival of hemodialysis patients requiring dialysis depends on the long-term functioning and patency of the vascular access. Prosthetic vascular grafts are inevitably used for patients whose vessels are unsuitable for an autogenous arteriovenous (AV) fistula. The purpose of this study was to compare the patency rate and associated complications using different types of grafts.

Methods: This prospective study was conducted on patients who did not have an appropriate vein for arteriovenous fistula from January 2004 through July 2006. They were divided into two groups, sex, age, and basic data matched. Polytetrafluoroethylene (PTFE) and polyurethane (PVAG) were the two types of grafts used in this study. The functionality of the graft was assessed immediately 1 day and 2 weeks after operation. The clinical follow-up was performed each 3 months until 24 months.

Results: One-year patency rate was reported to be 64% and 52% in the PTFE and PVAG groups, respectively. There was no significant difference in 1-year (64% versus 52%) and 2-year (49% versus 41%) patency rate of the PTFE and PVAG grafts used as vascular access. There was also no difference between the numbers of complications reported in the two groups.

Conclusion: It could be concluded that either PTFE or PVAG grafts can be used with the same expected outcomes.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Arteriovenous Fistula / therapy
  • Blood Vessel Prosthesis*
  • Catheters, Indwelling
  • Female
  • Humans
  • Male
  • Middle Aged
  • Polytetrafluoroethylene / therapeutic use*
  • Polyurethanes / therapeutic use*
  • Prospective Studies
  • Renal Dialysis / instrumentation*
  • Renal Dialysis / methods
  • Treatment Outcome
  • Vascular Patency*


  • Polyurethanes
  • Polytetrafluoroethylene