Dementia in a woman with Prader-Willi syndrome

Margje Sinnema; Constance T R M Schrander-Stumpel; Hans E G Verheij; Mireille Meeuwsen; Marian A Maaskant; Leopold M G Curfs

doi:10.1016/j.ejmg.2010.02.006

Dementia in a woman with Prader-Willi syndrome

Eur J Med Genet. 2010 May-Jun;53(3):145-8. doi: 10.1016/j.ejmg.2010.02.006. Epub 2010 Feb 26.

Authors

Margje Sinnema¹, Constance T R M Schrander-Stumpel, Hans E G Verheij, Mireille Meeuwsen, Marian A Maaskant, Leopold M G Curfs

Affiliation

¹ Department of Clinical Genetics, Maastricht University Medical Centre, Maastricht, The Netherlands. margje.sinnema@MUMC.nl

PMID: 20219703
DOI: 10.1016/j.ejmg.2010.02.006

Abstract

We report on a 58-year-old woman with Prader-Willi syndrome (PWS) and dementia. This case report illustrates a new research area in older adults with PWS. Dementia might be associated with PWS. In the case of dementia, more clinical studies are warranted to observe whether premature Alzheimer changes or indications of other dementia forms indeed occur more prevalent in people with PWS.

Publication types

Case Reports
Research Support, Non-U.S. Gov't

MeSH terms

Aging
Behavior
Communication
Dementia / complications*
Dementia / diagnosis*
Disease Progression
Female
Humans
Middle Aged
Prader-Willi Syndrome / complications*
Prader-Willi Syndrome / diagnosis*
Social Adjustment