[Chemical constituents from stems of Lonicera japonica]

Cong Zhang; Zhiqi Yin; Wencai Ye; Yuzhen Guan; Lian Guo; Jian Zhang; Wenbin Shen

[Chemical constituents from stems of Lonicera japonica]

Zhongguo Zhong Yao Za Zhi. 2009 Dec;34(23):3051-3.

[Article in Chinese]

Authors

Cong Zhang¹, Zhiqi Yin, Wencai Ye, Yuzhen Guan, Lian Guo, Jian Zhang, Wenbin Shen

Affiliation

¹ Department of Phytochemistry, China Pharmaceutical University, Nanjing 210009, China.

PMID: 20222422

Abstract

Objective: To investigate the chemical constituents from the ethanol extract of the stems of Lonicera japonica.

Method: The constituents were isolated and purified by repeated column chromatography on silica gel, Sephadex LH-20 and MCI HP-20. Their structures were identified by phsicochemical properties and spectroscopic analysis.

Result: Thirteen compounds were isolated and identified as protocatechuic acid (1), caffeic acid (2), macranthoin G (3), esculetin (4), luteolin (5), quercetin (6), apigenin (7), luteolin-7-O-beta-D-glucopyranoside (8), isorhamnetin-7-O-beta-D-glucopyranoside (9), diosmetin-7-O-beta-D-glucopyranoside (10), rhoifolin (11), lonicerin (12), hydnocarpin D (13).

Conclusion: Compound 4, 7, 9-11 were isolated from this plant for the first time, while compound 13 was first reported flavanolignan from this genus Lonicera.

Publication types

English Abstract
Research Support, Non-U.S. Gov't

MeSH terms

Luteolin / chemistry*
Plant Extracts / analysis*
Plant Extracts / isolation & purification
Plant Stems / chemistry

Substances

Plant Extracts
Luteolin