Isolation of ubiquitous Au(40)(SR)(24) clusters from the 8 kDa gold clusters

J Am Chem Soc. 2010 Apr 7;132(13):4583-5. doi: 10.1021/ja1006383.


We report chromatographic isolation of a new thiolate-protected gold cluster species from the approximately 8 kDa Au(n)(SR)(m) clusters. This new cluster is separated by size-exclusion chromatography from Au(38)(SC(2)H(4)Ph)(24) (a previously reported main component in the approximately 8 kDa gold-thiolate species). Based on detailed MALDI and ESI mass spectrometry analyses, the new cluster possesses a core mass of approximately 8.6 kDa and its formula is determined to be Au(40)(SC(2)H(4)Ph)(24). The Au(40)(SR)(24) species is also found to exist in other thiolate systems, including -SR=SC(6)H(13) and SC(5)H(11), indicating that Au(40)(SR)(24) is a ubiquitous cluster as is Au(38)(SR)(24).

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Gold / chemistry*
  • Mass Spectrometry
  • Metal Nanoparticles / chemistry*
  • Organogold Compounds / chemical synthesis
  • Organogold Compounds / chemistry*
  • Organogold Compounds / isolation & purification*


  • Organogold Compounds
  • Gold