[How often is the Depersonalization-Derealization Disorder (ICD-10: F48.1) diagnosed in the outpatient health-care service?]

Z Psychosom Med Psychother. 2010;56(1):74-83. doi: 10.13109/zptm.2010.56.1.74.
[Article in German]


Objectives: The study determines how often Depersonalization-Derealization Disorder (ICD-10: F48.1) is diagnosed in the general population and analyzes the associations of other diseases with F48.1.

Methods: The sample consists of 1.567 million insured persons of a statutory health insurance fund in Germany. We analyzed the prevalence of F48.1 and the associations of F48.1 with other diseases according to ICD-10.

Results: We found a 1-year prevalence of 0.007 % for the diagnosis of F48.1. After adjustment for age, sex, depression and anxiety, several somatic disease groups were found to be associated with an increased likelihood of F48.1, e.g., abnormalities of breathing (R06), cardiac arrhythmias (I47-I49), epilepsy (G40), dizziness (H81, H82, R42) and headache (G43, G44, R51).

Conclusions: According to epidemiological studies, the prevalence of depersonalization-derealization disorder is 1-2 %. We therefore conclude that F48.1 is severely underdiagnosed. Increased awareness for the detection of F48.1 and further health care research are urgently warranted.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Ambulatory Care / statistics & numerical data*
  • Anxiety Disorders / diagnosis
  • Anxiety Disorders / epidemiology
  • Anxiety Disorders / psychology
  • Child
  • Comorbidity
  • Cross-Sectional Studies
  • Depersonalization / diagnosis*
  • Depersonalization / epidemiology*
  • Depressive Disorder / diagnosis
  • Depressive Disorder / epidemiology
  • Depressive Disorder / psychology
  • Female
  • Germany
  • Humans
  • Incidence
  • International Classification of Diseases
  • Male
  • Middle Aged
  • Population Surveillance
  • Psychophysiologic Disorders / diagnosis
  • Psychophysiologic Disorders / epidemiology
  • Psychophysiologic Disorders / psychology
  • Young Adult