Microsurgery for lymphedema: clinical research and long-term results

Microsurgery. 2010 May;30(4):256-60. doi: 10.1002/micr.20737.

Abstract

Objectives: To report the wide clinical experience and the research studies in the microsurgical treatment of peripheral lymphedema.

Methods: More than 1800 patients with peripheral lymphedema have been treated with microsurgical techniques. Derivative lymphatic microvascular procedures recognize today its most exemplary application in multiple lymphatic-venous anastomoses (LVA). In case of associated venous disease reconstructive lymphatic microsurgery techniques have been developed. Objective assessment was undertaken by water volumetry and lymphoscintigraphy.

Results: Subjective improvement was noted in 87% of patients. Objectively, volume changes showed a significant improvement in 83%, with an average reduction of 67% of the excess volume. Of those patients followed-up, 85% have been able to discontinue the use of conservative measures, with an average follow-up of more than 10 years and average reduction in excess volume of 69%. There was a 87% reduction in the incidence of cellulitis after microsurgery.

Conclusions: Microsurgical LVA have a place in the treatment of peripheral lymphedema, and should be the therapy of choice in patients who are not sufficiently responsive to nonsurgical treatment.

Publication types

  • Evaluation Study

MeSH terms

  • Anastomosis, Surgical
  • Biomedical Research
  • Cohort Studies
  • Female
  • Follow-Up Studies
  • Humans
  • Italy
  • Lymphatic Vessels / diagnostic imaging
  • Lymphatic Vessels / surgery*
  • Lymphedema / diagnostic imaging
  • Lymphedema / surgery*
  • Male
  • Microsurgery / methods*
  • Plastic Surgery Procedures / methods
  • Radionuclide Imaging
  • Retrospective Studies
  • Risk Assessment
  • Severity of Illness Index
  • Time
  • Treatment Outcome