High prevalence of vitamin D deficiency among inner-city African American youth with asthma in Washington, DC

J Pediatr. 2010 Jun;156(6):948-952. doi: 10.1016/j.jpeds.2009.12.033. Epub 2010 Mar 16.

Abstract

Objective: The goal of this study was to examine the prevalence of vitamin D insufficiency and deficiency among urban African-American (AA) youth with asthma compared with control subjects without asthma.

Study design: A cross-sectional case-control study was conducted at an urban pediatric medical center. Total 25-hydroxyvitamin D insufficiency (<30 ng/mL) and deficiency (<20 ng/mL) were assessed in urban self-reported AA patients, aged 6 to 20 years, with (n = 92) and without (n = 21) physician-diagnosed asthma.

Results: Blood samples were available for 85 (92%) cases. The prevalence of vitamin D insufficiency and deficiency were significantly greater among cases than control subjects (73/85 [86%] vs 4/21 [19%], adjusted odds ratio = 42 [95% confidence interval: 4.4 to 399] for insufficiency and 46/85 [54%] vs 1/21 [5%], adjusted odds ratio = 20 [95% confidence interval: 1.4 to 272] for deficiency).

Conclusions: Most of this sample of urban AA youth with persistent asthma were vitamin D deficient or insufficient. Given the emerging associations between low vitamin D levels and asthma, strong consideration should be given to routine vitamin D testing in urban AA youth, particularly those with asthma.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • African Americans / statistics & numerical data*
  • Asthma / epidemiology*
  • Case-Control Studies
  • Child
  • Cross-Sectional Studies
  • District of Columbia / epidemiology
  • Female
  • Humans
  • Male
  • Seasons
  • Urban Population
  • Vitamin D Deficiency / epidemiology*
  • Young Adult