A pterocarpan from the seeds of Bituminaria morisiana

J Nat Med. 2010 Jul;64(3):354-7. doi: 10.1007/s11418-010-0408-7. Epub 2010 Mar 18.

Abstract

A new prenylated pterocarpan, named morisianine, was isolated together with the known secondary metabolites erybraedin C, psoralen and angelicin from the seeds of Bituminaria morisiana. The structures of the compounds were elucidated mainly by 1D and 2D NMR experiments as well as mass spectrometry. The new compound was subjected to cytotoxicity screening against a panel of human cancer cells.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Caco-2 Cells
  • Cell Line, Tumor
  • Cell Survival / drug effects
  • Fabaceae / chemistry*
  • Ficusin / chemistry
  • Furocoumarins / chemistry
  • HL-60 Cells
  • Humans
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Pterocarpans / chemistry*
  • Pterocarpans / pharmacology
  • Seeds / chemistry*

Substances

  • Furocoumarins
  • Pterocarpans
  • erybraedin C
  • angelicin
  • Ficusin