Abstract
A novel antibiotic, designated lydicamycin, was isolated from the fermentation broth of an actinomycete strain identified as Streptomyces lydicus. Lydicamycin was active against Gram-positive bacteria and a certain yeast, but inactive against Gram-negative bacteria.
MeSH terms
-
Anti-Bacterial Agents / biosynthesis*
-
Anti-Bacterial Agents / isolation & purification
-
Anti-Bacterial Agents / pharmacology
-
Cryptococcus neoformans / drug effects*
-
Fatty Alcohols / pharmacology
-
Fermentation
-
Gram-Positive Bacteria / drug effects*
-
Methicillin Resistance
-
Microscopy, Electron
-
Molecular Structure
-
Pyrrolidinones / pharmacology
-
Soil Microbiology
-
Staphylococcus aureus / drug effects
-
Streptomyces / classification*
-
Streptomyces / metabolism
-
Streptomyces / ultrastructure
Substances
-
Anti-Bacterial Agents
-
Fatty Alcohols
-
Pyrrolidinones
-
lydicamycin