Comparison of post amputation outcome in patients with type 2 diabetes from specialized foot care centres in three developing countries

Diabetes Res Clin Pract. 2010 May;88(2):146-50. doi: 10.1016/j.diabres.2010.02.015. Epub 2010 Mar 17.


Objective: To evaluate post amputation outcome and associated complications in type 2 diabetic patients who had undergone major amputations in developing countries.

Patients and methods: A total of 526 (M:F; 369:157) subjects from three centers [India (IND), n=194, Bangladesh (BAN) n=177 and Tanzania (TAN) n=155 who had undergone amputation and subsequently visited the hospital were included in this analysis. Details on foot problems and associated complications were recorded.

Results: The prevalence of amputations was similar in all centres. The history of minor amputation and foot deformity was high in BAN. Recurrence of foot ulceration was more in TAN (30%) than in IND (9%) and BAN (11%). Re-amputation rate was similar in all groups (3%). The use of artificial limb was most in BAN (97%). Myocardial infarction was more prevalent in IND (15%). In Tanzania, 31% had died during the follow-up period and it was 16% and 5% in IND and BAN. The causes of death were infection due to septicemia and cardiovascular events which finally led to multisystem organ failure.

Conclusion: The outcome following a major diabetic foot amputation was compared in three developing countries. Recurrence of foot infection was common in Tanzania. The most frequent causes of death were infection and cardiovascular events.

Publication types

  • Comparative Study
  • Multicenter Study

MeSH terms

  • Aged
  • Amputation, Surgical*
  • Bangladesh / epidemiology
  • Cardiovascular Diseases
  • Cause of Death
  • Developing Countries
  • Diabetes Mellitus, Type 2 / complications*
  • Diabetic Foot / epidemiology
  • Diabetic Foot / surgery*
  • Female
  • Humans
  • India / epidemiology
  • Infections
  • Male
  • Middle Aged
  • Recurrence
  • Tanzania / epidemiology
  • Treatment Outcome