Botulinum Toxin: Non-cosmetic Indications and Possible Mechanisms of Action

J Cutan Aesthet Surg. 2008 Jan;1(1):3-6. doi: 10.4103/0974-2077.41148.


Botulinum toxin (BTX) has gained a great interest in cosmetic dermatology for its effects on hyperkinetic facial lines. Understanding the basic research and analysis of effects of this potent drug can lead to other possible indications of interest for dermatologists. The use of BTX in focal hyperhidrosis is well established, but BTX has also effects on pain perception, itch and inflammation as discussed in this review.

Keywords: Acetylcholine; Botulinum toxin; SNARE complex.