The purpose of this overview is to:
Define the clinical characteristics of thoracic aortic disease;
Review the causes of heritable thoracic aortic disease;
Provide a strategy for evaluation and genetic risk assessment for heritable thoracic aortic disease in a proband;
Review management recommendations for individuals with heritable thoracic aortic disease;
Inform genetic counseling and risk assessment in family members of a proband with heritable thoracic aortic disease.
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