Monogenic Parkinson Disease Overview

Excerpt

The purpose of this overview is to:

1. 1

   Describe the clinical characteristics of Parkinson disease;

2. 2

   Review monogenic causes of Parkinson disease;

3. 3

   Review the differential diagnosis of monogenic Parkinson disease;

4. 4

   Provide an evaluation strategy to identify the cause of monogenic Parkinson disease in a proband;

5. 5

   Provide information on targeted therapeutic clinical trials for Parkinson disease;

6. 6

   Inform genetic counseling for family members of an individual with monogenic Parkinson disease.